Acquire this medication by mouth with or without food items with an entire glass of drinking water (8 ounces or 240 milliliters) or as directed by your health practitioner. This medication could possibly be taken with foods or milk if stomach upset occurs. The dosage is predicated in your healthcare affliction and response to remedy.
Because opioid agonists may possibly increase biliary tract strain, with resultant boost in plasma amylase or lipase levels, perseverance of such enzyme ranges can be unreliable for twenty-four hours soon after administration of the dose of Promethazine HCl and Codeine Phosphate Oral Solution.
Prolonged-expression utilization of promethazine/codeine may well have an affect on your ability to turn out to be pregnant or obtain a companion Expecting. Talk with your healthcare provider When you have any considerations.
Epinephrine - Due to likely for promethazine to reverse epinephrine’s vasopressor influence, epinephrine should NOT be employed to treat hypotension involved with promethazine overdose.
People who find themselves sixty five and more mature is usually at bigger risk for some Unwanted effects from promethazine/codeine. Check with your Health care provider regarding your dangers Should you be During this age team.
Promethazine hydrochloride was not mutagenic in the in vitro bacterial reverse mutation assay or clastogenic during the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay.
Other challenges of codeine-based mostly goods involve Bodily dependence and addiction. With a Bodily dependence on codeine, someone has employed the drug for a length of time until finally their body looks like it needs codeine to operate Usually.
The precise system of action of codeine and other opiates just isn't known; nonetheless, codeine is considered to act centrally within the cough Heart. In extreme doses, codeine will depress respiration.
Because of this, and taking into account the stories Now we have gained in relation to abuse, We've got reclassified codeine linctus into a click here prescription-only drugs for the advantage of patients, carers and healthcare professionals throughout the United kingdom.
Sedating prescription drugs could result in confusion and above-sedation inside get more info the elderly; elderly individuals commonly must be began on minimal doses of Promethazine Hydrochloride and Codeine Phosphate website Syrup and noticed intently.
We welcome the choice to reclassify codeine linctus to a prescription-only medication for a constructive stage to protect affected individual basic safety.
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。
Codeine has superior antitussive activity, While lower than that of morphine at equal doses. It is actually Utilized in preference to morphine, due to the fact Uncomfortable side effects are infrequent at the read more usual antitussive dose of codeine.
Focus–Adverse Response Relationships You will find a romance involving rising codeine plasma concentration and raising frequency of dose- connected opioid adverse reactions such as nausea, vomiting, CNS results, and here respiratory despair.